Constitutive high expression of NOXA sensitizes human embryonic stem cells for rapid cell death
Constitutive high expression of NOXA sensitizes human embryonic stem cells for rapid cell death
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract Human embryonic stem (hES) cells are highly sensitive to apoptotic stimuli such as DNA damage, which allows for rapid elimination of mutated cells during development. However, the mechanisms that maintain hES cells in the primed apoptotic state are not completely known. Key activators of apoptosis, the BH3-only proteins, are present at low...
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Constitutive high expression of NOXA sensitizes human embryonic stem cells for rapid cell death
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TN_cdi_proquest_journals_2506557899
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2506557899
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E-ISSN
2692-8205
DOI
10.1101/2021.01.13.426566
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https://www.proquest.com/docview/2506557899?pq-origsite=primo&accountid=13902
