Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation
Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation
About this item
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Author / Creator
Quintanal-Villalonga, Alvaro , Taniguchi, Hirozaku , Zhan, Yingqian A , Hasan, Maysun M , Meng, Fanli , Uddin, Fathema , Donoghue, Mark , Won, Helen H , Chavan, Shweta S , Chan, Joseph M , Ciampricotti, Metamia , Chow, Andrew , Offin, Michael , Chang, Jason C , Ray-Kirton, Jordana , Egger, Jacklynn , Bhanot, Umesh K , Silber, Joachim , Iacobuzio-Donahue, Christine A , Roehrl, Michael H , Hollmann, Travis J , Yu, Helena A , Rekhtman, Natasha , Poirier, John T , Houck-Loomis, Brian , Koche, Richard P , Rudin, Charles M and Sen, Triparna
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
ABSTRACT Lineage plasticity, a capacity to reprogram cell phenotypic identity under evolutionary pressure, is implicated in treatment resistance and metastasis in multiple cancers. In lung adenocarcinomas (LUADs) amenable to treatment with targeted inhibitors, transformation to an aggressive neuroendocrine (NE) carcinoma resembling small cell lung...
Alternative Titles
Full title
Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation
Authors, Artists and Contributors
Author / Creator
Taniguchi, Hirozaku
Zhan, Yingqian A
Hasan, Maysun M
Meng, Fanli
Uddin, Fathema
Donoghue, Mark
Won, Helen H
Chavan, Shweta S
Chan, Joseph M
Ciampricotti, Metamia
Chow, Andrew
Offin, Michael
Chang, Jason C
Ray-Kirton, Jordana
Egger, Jacklynn
Bhanot, Umesh K
Silber, Joachim
Iacobuzio-Donahue, Christine A
Roehrl, Michael H
Hollmann, Travis J
Yu, Helena A
Rekhtman, Natasha
Poirier, John T
Houck-Loomis, Brian
Koche, Richard P
Rudin, Charles M
Sen, Triparna
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2506868556
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2506868556
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2020.12.02.408476
How to access this item
https://www.proquest.com/docview/2506868556?pq-origsite=primo&accountid=13902
