Intestinal ferritinophagy is regulated by HIF-2α and is essential for systemic iron homeostasis
Intestinal ferritinophagy is regulated by HIF-2α and is essential for systemic iron homeostasis
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract Iron is critical for many processes including oxygen transport and erythropoiesis. Transcriptomic analysis demonstrates that HIF-2α regulates over 90% of all transcripts induced following iron deficiency in the intestine. However, beyond divalent metal transporter 1 (DMT1), ferroportin 1 (Fpn1) and duodenal cytochrome b (Dcytb), no other g...
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Intestinal ferritinophagy is regulated by HIF-2α and is essential for systemic iron homeostasis
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TN_cdi_proquest_journals_2506883591
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2506883591
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E-ISSN
2692-8205
DOI
10.1101/2020.11.01.364059
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https://www.proquest.com/docview/2506883591?pq-origsite=primo&accountid=13902
