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Spatial heterogeneity of glioblastoma cells reveals sensitivity to NAD+ depletion at tumor edge

Spatial heterogeneity of glioblastoma cells reveals sensitivity to NAD+ depletion at tumor edge

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2507133676

Spatial heterogeneity of glioblastoma cells reveals sensitivity to NAD+ depletion at tumor edge

About this item

Full title

Spatial heterogeneity of glioblastoma cells reveals sensitivity to NAD+ depletion at tumor edge

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-11

Language

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

ABSTRACT Even after total resection of glioblastoma core lesions by surgery and aggressive post-surgical treatments, life-threatening tumors inevitably recur. A characteristic obstacle in effective treatment is high intratumoral heterogeneity, both longitudinally and spatially. Recurrence occurs predominantly at the brain parenchyma-tumor core inte...

Alternative Titles

Full title

Spatial heterogeneity of glioblastoma cells reveals sensitivity to NAD+ depletion at tumor edge

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2507133676

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2507133676

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.11.26.399725