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Subtractive CRISPR screen identifies factors involved in non-canonical LC3 lipidation

Subtractive CRISPR screen identifies factors involved in non-canonical LC3 lipidation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2507164522

Subtractive CRISPR screen identifies factors involved in non-canonical LC3 lipidation

About this item

Full title

Subtractive CRISPR screen identifies factors involved in non-canonical LC3 lipidation

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract Although commonly associated with autophagosomes, LC3 can also be recruited to membranes in a variety of non-canonical contexts. These include responses to ionophores such as the M2 proton channel of influenza A virus. LC3 is attached to membranes by covalent lipidation that depends on recruitment of the ATG5-12-16L1 complex. Non-canonical...

Alternative Titles

Full title

Subtractive CRISPR screen identifies factors involved in non-canonical LC3 lipidation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2507164522

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2507164522

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.11.18.388306