Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T...
Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells
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United States: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
United States: Cold Spring Harbor Laboratory Press
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Contents
While inhibition of T cell co-inhibitory receptors has revolutionized cancer therapy, the mechanisms governing their expression on human T cells have not been elucidated. Type 1 interferon (IFN-I) modulates T cell immunity in viral infection, autoimmunity, and cancer, and may facilitate induction of T cell exhaustion in chronic viral infection
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Full title
Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells
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TN_cdi_proquest_journals_2507289081
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2507289081
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E-ISSN
2692-8205
DOI
10.1101/2020.10.30.362947
