APOEε3/ε4 and APOEε4/ε4 genotypes drive unique gene signatures in the cortex of young mice
APOEε3/ε4 and APOEε4/ε4 genotypes drive unique gene signatures in the cortex of young mice
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract Background Restrictions on mouse models have significantly impacted research towards understanding the most common genotype contributing to dementia in the human population – APOEε3/ε4. To address this, as part of MODEL-AD, we created new versions of humanized APOEε4 and APOEε3 mice on a C57BL/6J background that allow for unrestricted dist...
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APOEε3/ε4 and APOEε4/ε4 genotypes drive unique gene signatures in the cortex of young mice
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TN_cdi_proquest_journals_2507750086
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2507750086
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E-ISSN
2692-8205
DOI
10.1101/2020.10.28.359422
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https://www.proquest.com/docview/2507750086?pq-origsite=primo&accountid=13902
