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Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2507824279

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract Lineage plasticity, the ability of a cell to alter its identity, is an increasingly common mechanism of adaptive resistance to targeted therapy in cancer1,2. An archetypal example is the development of neuroendocrine prostate cancer (NEPC) after treatment of prostate adenocarcinoma (PRAD) with inhibitors of androgen signaling. NEPC is an a...

Alternative Titles

Full title

Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2507824279

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2507824279

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.10.23.350793