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Characterization of the signalling modalities of prostaglandin E2 receptors EP2 and EP4 reveals cros...

Characterization of the signalling modalities of prostaglandin E2 receptors EP2 and EP4 reveals cros...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508008233

Characterization of the signalling modalities of prostaglandin E2 receptors EP2 and EP4 reveals crosstalk and a role for microtubules

About this item

Full title

Characterization of the signalling modalities of prostaglandin E2 receptors EP2 and EP4 reveals crosstalk and a role for microtubules

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract Prostaglandin E2 (PGE2) is a lipid mediator that modulates the function of myeloid immune cells such as macrophages and dendritic cells (DCs) through the activation of the G protein-coupled receptors EP2 and EP4. While both EP2 and EP4 signalling leads to an elevation of intracellular cyclic adenosine monophosphate (cAMP) levels through th...

Alternative Titles

Full title

Characterization of the signalling modalities of prostaglandin E2 receptors EP2 and EP4 reveals crosstalk and a role for microtubules

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2508008233

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508008233

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.10.06.328351