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Lung macrophages mediate helminth resistance through differential activation of recruited monocyte-d...

Lung macrophages mediate helminth resistance through differential activation of recruited monocyte-d...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508017733

Lung macrophages mediate helminth resistance through differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion

About this item

Full title

Lung macrophages mediate helminth resistance through differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Macrophages are known to mediate anti-helminth responses, but it remains uncertain which subsets are involved or how macrophages actually kill helminths. Here we show rapid monocyte recruitment to the lung after infection with the nematode parasite, Nippostrongylus brasiliensis. In this inflamed tissue microenvironment these monocytes differentiate...

Alternative Titles

Full title

Lung macrophages mediate helminth resistance through differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2508017733

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508017733

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.10.02.322388