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Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy

Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508019230

Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy

About this item

Full title

Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract Strain 68-1 rhesus cytomegalovirus (RhCMV) vectors expressing simian immunodeficiency virus (SIV) antigens elicit CD8+ T cells that recognize peptide epitopes presented by major histocompatibility complex (MHC)-II and MHC-E molecules, instead of MHC-Ia, and are uniquely able to mediate stringent control and subsequent clearance of highly p...

Alternative Titles

Full title

Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2508019230

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508019230

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.09.30.321158