α-Endosulfine regulates amyloid β 42 via the modulation of neprilysin activity
α-Endosulfine regulates amyloid β 42 via the modulation of neprilysin activity
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract The neuropeptide somatostatin (SST) regulates amyloid β peptide (Aβ) catabolism by enhancing neprilysin (NEP)-catalyzed proteolytic degradation. However, the mechanism by which SST regulates NEP activity remains unclear. Here we report the identification by differential proteomics of α-endosulfine (ENSA), an endogenous ligand of the ATP-se...
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α-Endosulfine regulates amyloid β 42 via the modulation of neprilysin activity
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TN_cdi_proquest_journals_2508120680
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508120680
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2692-8205
DOI
10.1101/2020.10.07.329318
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https://www.proquest.com/docview/2508120680?pq-origsite=primo&accountid=13902