Log in to save to my catalogue

α-Endosulfine regulates amyloid β 42 via the modulation of neprilysin activity

α-Endosulfine regulates amyloid β 42 via the modulation of neprilysin activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508120680

α-Endosulfine regulates amyloid β 42 via the modulation of neprilysin activity

About this item

Full title

α-Endosulfine regulates amyloid β 42 via the modulation of neprilysin activity

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract The neuropeptide somatostatin (SST) regulates amyloid β peptide (Aβ) catabolism by enhancing neprilysin (NEP)-catalyzed proteolytic degradation. However, the mechanism by which SST regulates NEP activity remains unclear. Here we report the identification by differential proteomics of α-endosulfine (ENSA), an endogenous ligand of the ATP-se...

Alternative Titles

Full title

α-Endosulfine regulates amyloid β 42 via the modulation of neprilysin activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2508120680

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508120680

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.10.07.329318