A cross-species link between mTOR-related synaptic pathology and functional hyperconnectivity in aut...
A cross-species link between mTOR-related synaptic pathology and functional hyperconnectivity in autism
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Author / Creator
Pagani, Marco , Bertero, Alice , Trakoshis, Stavros , Ulysse, Laura , Locarno, Andrea , Miseviciute, Ieva , De Felice, Alessia , Canella, Carola , Supekar, Kausthub , Galbusera, Alberto , Menon, Vinod , Tonini, Raffaella , Deco, Gustavo , Lombardo, Michael V , Pasqualetti, Massimo and Gozzi, Alessandro
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Abstract Postmortem studies have revealed increased density of excitatory synapses in the brains of individuals with autism, with a putative link to aberrant mTOR-dependent synaptic pruning. Autism is also characterized by atypical macroscale functional connectivity as measured with resting-state fMRI (rsfMRI). These observations raise the question...
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Full title
A cross-species link between mTOR-related synaptic pathology and functional hyperconnectivity in autism
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TN_cdi_proquest_journals_2508120928
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508120928
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E-ISSN
2692-8205
DOI
10.1101/2020.10.07.329292
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https://www.proquest.com/docview/2508120928?pq-origsite=primo&accountid=13902
