β-adrenergic control of sarcolemmal CaV1.2 abundance by small GTPase Rab proteins
β-adrenergic control of sarcolemmal CaV1.2 abundance by small GTPase Rab proteins
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract The number and activity of Cav1.2 channels in the cardiomyocyte sarcolemma tunes the magnitude of Ca2+-induced Ca2+ release and myocardial contraction. β-adrenergic receptor (βAR) activation stimulates sarcolemmal insertion of CaV1.2 channels. This supplements the pre-existing sarcolemmal CaV1.2 population, forming large ‘super-clusters’ w...
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Full title
β-adrenergic control of sarcolemmal CaV1.2 abundance by small GTPase Rab proteins
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TN_cdi_proquest_journals_2508125875
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508125875
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E-ISSN
2692-8205
DOI
10.1101/2020.09.28.317362
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https://www.proquest.com/docview/2508125875?pq-origsite=primo&accountid=13902