Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibil...
Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model
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Author / Creator
Lee, Leo Yy , Zhou, Jie , Koszalka, Paulina , Frise, Rebecca , Farrukee, Rubaiyea , Baba, Keiko , Miah, Shahjahan , Shishido, Takao , Galiano, Monica , Hashimoto, Takashi , Omoto, Shinya , Uehara, Takeki , Mifsud, Edin , Collinson, Neil , Kuhlbusch, Klaus , Clinch, Barry , Wildum, Steffen , Barclay, Wendy and Hurt, Aeron C
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract Baloxavir is approved in several countries for the treatment of uncomplicated influenza in otherwise-healthy and high-risk patients. Treatment-emergent viruses with reduced susceptibility to baloxavir have been detected in clinical trials, but the likelihood of widespread occurrence depends on replication capacity and onward transmission....
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Full title
Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model
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TN_cdi_proquest_journals_2508126060
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508126060
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E-ISSN
2692-8205
DOI
10.1101/2020.09.28.316620
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https://www.proquest.com/docview/2508126060?pq-origsite=primo&accountid=13902
