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Proneural genes define ground state rules to regulate neurogenic patterning and cortical folding

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Proneural genes define ground state rules to regulate neurogenic patterning and cortical folding

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508140496

Proneural genes define ground state rules to regulate neurogenic patterning and cortical folding

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Cold Spring Harbor: Cold Spring Harbor Laboratory Press

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Contents

Neurog2 and Ascl1 proneural genes regulate cortical progenitor cell differentiation through cross-repressive interactions to sustain neurogenic continuity in a lissencephalic rodent brain. Using in vivo lineage tracing, we found that Neurog2 and Ascl1 expression defines a lineage continuum of four progenitor pools, with ‘double+ progenitors’ displa...

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Full title

Proneural genes define ground state rules to regulate neurogenic patterning and cortical folding

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TN_cdi_proquest_journals_2508140496

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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508140496

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E-ISSN

2692-8205

DOI

10.1101/2020.09.22.307058

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