ImmunoCluster: A computational framework for the non-specialist to profile cellular heterogeneity in...
ImmunoCluster: A computational framework for the non-specialist to profile cellular heterogeneity in cytometry datasets
About this item
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Author / Creator
Opzoomer, James W , Timms, Jessica , Blighe, Kevin , Mourikis, Thanos P , Chapuis, Nicolas , Bekoe, Richard , Kareemaghay, Sedigeh , Nocerino, Paola , Apollonio, Benedetta , Ramsay, Alan G , Tavassoli, Mahvash , Harrison, Claire , Ciccarelli, Francesca , Parker, Peter , Fontenay, Michaela , Barber, Paul R , Arnold, James N and Kordasti, Shahram
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Abstract High dimensional cytometry is an innovative tool for immune monitoring in health and disease, it has provided novel insight into the underlying biology as well as biomarkers for a variety of diseases. However, the analysis of multiparametric “big data” usually requires specialist computational knowledge. Here we describe ImmunoCluster (https://github.com/kordastilab/ImmunoCluster) an R package for immune profiling cellular heterogeneity in high dimensional liquid and imaging mass cytometry, and flow cytometry data, designed to facilitate computational analysis by a non-specialist. The analysis framework implemented within ImmunoCluster is readily scalable to millions of cells and provides a variety of visualization and...
Alternative Titles
Full title
ImmunoCluster: A computational framework for the non-specialist to profile cellular heterogeneity in cytometry datasets
Authors, Artists and Contributors
Author / Creator
Timms, Jessica
Blighe, Kevin
Mourikis, Thanos P
Chapuis, Nicolas
Bekoe, Richard
Kareemaghay, Sedigeh
Nocerino, Paola
Apollonio, Benedetta
Ramsay, Alan G
Tavassoli, Mahvash
Harrison, Claire
Ciccarelli, Francesca
Parker, Peter
Fontenay, Michaela
Barber, Paul R
Arnold, James N
Kordasti, Shahram
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2508166072
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508166072
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2020.09.09.289033
How to access this item
https://www.proquest.com/docview/2508166072?pq-origsite=primo&accountid=13902
