Antifungal benzimidazoles disrupt vasculature by targeting one of nine β-tubulins
Antifungal benzimidazoles disrupt vasculature by targeting one of nine β-tubulins
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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ABSTRACT Thiabendazole (TBZ) is an FDA-approved benzimidazole widely used for its antifungal and antihelminthic properties. We showed previously that TBZ is also a potent vascular disrupting agent and inhibits angiogenesis at the tissue level by dissociating vascular endothelial cells in newly formed blood vessels. Here, we uncover TBZ’s molecular...
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Antifungal benzimidazoles disrupt vasculature by targeting one of nine β-tubulins
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TN_cdi_proquest_journals_2508229772
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508229772
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E-ISSN
2692-8205
DOI
10.1101/2020.09.15.298828
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https://www.proquest.com/docview/2508229772?pq-origsite=primo&accountid=13902
