In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulator...
In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Vertebrate genomes organize into topologically associating domains (TADs), delimited by boundaries that insulate regulatory elements from non-target genes. However, how boundary function is established is not well understood. Here, we combine genome-wide analyses and transgenic mouse assays to dissect the regulatory logic of clustered-CTCF boundari...
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Full title
In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation
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TN_cdi_proquest_journals_2512583534
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2512583534
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E-ISSN
2692-8205
DOI
10.1101/2021.04.14.439779
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https://www.proquest.com/docview/2512583534?pq-origsite=primo&accountid=13902
