Chiral Transplacental Pharmacokinetics of Fexofenadine: Impact of P-Glycoprotein Inhibitor Fluoxetin...
Chiral Transplacental Pharmacokinetics of Fexofenadine: Impact of P-Glycoprotein Inhibitor Fluoxetine Using the Human Placental Perfusion Model
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Contents
Purpose
Fexofenadine is a well-identified
in vivo
probe substrate of P-glycoprotein (P-gp) and/or organic anion transporting polypeptide (OATP). This work aimed to investigate the transplacental pharmacokinetics of fexofenadine enantiomers with and without the selective P-gp inhibitor fluoxetine.
Methods
The chiral transplacental pha...
Alternative Titles
Full title
Chiral Transplacental Pharmacokinetics of Fexofenadine: Impact of P-Glycoprotein Inhibitor Fluoxetine Using the Human Placental Perfusion Model
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TN_cdi_proquest_journals_2515482500
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2515482500
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ISSN
0724-8741
E-ISSN
1573-904X
DOI
10.1007/s11095-021-03035-7
