Toxicokinetics of the tumour cell mitochondrial toxin, PENAO, in rodents
Toxicokinetics of the tumour cell mitochondrial toxin, PENAO, in rodents
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New York: Springer US
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English
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New York: Springer US
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Summary
PENAO (4-(N-(S-penicillaminylacetyl)amino)phenylarsonous acid) is a second-generation peptide arsenical that inactivates mitochondria in proliferating tumour cells by covalently reacting with mitochondrial inner-membrane adenine nucleotide transferase. The toxicokinetics of PENAO has been investigated in Sprague-Dawley rats to inform rou...
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Toxicokinetics of the tumour cell mitochondrial toxin, PENAO, in rodents
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TN_cdi_proquest_journals_2517673802
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2517673802
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ISSN
0167-6997
E-ISSN
1573-0646
DOI
10.1007/s10637-021-01065-x