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IRE1α governs cytoskeleton remodelling and cell migrationthrough a direct interaction with filamin A

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IRE1α governs cytoskeleton remodelling and cell migrationthrough a direct interaction with filamin A

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2518557428

IRE1α governs cytoskeleton remodelling and cell migrationthrough a direct interaction with filamin A

About this item

Full title

IRE1α governs cytoskeleton remodelling and cell migrationthrough a direct interaction with filamin A

Author / Creator

Urra Hery , Henriquez, Daniel R , Cánovas José , Villarroel-Campos, David , Carreras-Sureda Amado , Pulgar Eduardo , Molina, Emiliano , Hazari, Younis M , Limia, Celia M , Alvarez-Rojas, Sebastián , Figueroa, Ricardo , Vidal, Rene L , Rodriguez, Diego A , Rivera, Claudia A , Court, Felipe A , Couve Andrés , Ling, Qi , Chevet, Eric , Akai Ryoko , Iwawaki Takao , Concha, Miguel L , Glavic Álvaro , Gonzalez-Billault, Christian and Hetz Claudio

Publisher

London: Nature Publishing Group

Journal title

Nature cell biology, 2018-08, Vol.20 (8), p.942-953

Language

English

Formats

Articles

Publication information

Publisher

London: Nature Publishing Group

Subjects

More information

Scope and Contents

Contents

Maintenance of endoplasmic reticulum (ER) proteostasis is controlled by a signalling network known as the unfolded protein response (UPR). Here, we identified filamin A as a major binding partner of the ER stress transducer IRE1α. Filamin A is an actin crosslinking factor involved in cytoskeleton remodelling. We show that IRE1α controls actin cytos...

Alternative Titles

Full title

IRE1α governs cytoskeleton remodelling and cell migrationthrough a direct interaction with filamin A

Authors, Artists and Contributors

Author / Creator

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Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2518557428

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2518557428

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/s41556-018-0141-0

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