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Modeling breast cancer by grafting patient tumor samples in the avian embryo: an in vivo platform fo...

Modeling breast cancer by grafting patient tumor samples in the avian embryo: an in vivo platform fo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2518859763

Modeling breast cancer by grafting patient tumor samples in the avian embryo: an in vivo platform for therapy evaluation coupled to large scale molecular analyses

About this item

Full title

Modeling breast cancer by grafting patient tumor samples in the avian embryo: an in vivo platform for therapy evaluation coupled to large scale molecular analyses

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-04

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Lack of preclinical patient-derived xenograft (PDX) cancer models in which to conduct large scale molecular studies seriously impairs the development of effective personalized therapies. We report here on an in vivo concept consisting of implanting human tumor cells in targeted tissues of an avian embryo, delivering therapeutics, evaluating their e...

Alternative Titles

Full title

Modeling breast cancer by grafting patient tumor samples in the avian embryo: an in vivo platform for therapy evaluation coupled to large scale molecular analyses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2518859763

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2518859763

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.04.26.441511