Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19
Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19
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Author / Creator
Apostolidis, Sokratis A , Sarkar, Amrita , Giannini, Heather M , Goel, Rishi R , Mathew, Divij , Suzuki, Aae , Baxter, Amy E , Greenplate, Allison R , Alanio, Cécile , Abdel-Hakeem, Mohamed , Oldridge, Derek A , Giles, Josephine , Wu, Jennifer E , Chen, Zeyu , Huang, Yinghui Jane , Pattekar, Ajinkya , Manne, Sasikanth , Kuthuru, Oliva , Dougherty, Jeanette , Weiderhold, Brittany , Weisman, Ariel R , Ittner, Caroline A G , Gouma, Sigrid , Dunbar, Debora , Frank, Ian , Huang, Alexander C , Vella, Laura A , Reilly, John P , Hensley, Scott E , Rauova, Lubica , Zhao, Liang , Meyer, Nuala J , Poncz, Mortimer , Abrams, Charles S , Wherry, E John and UPenn COVID Processing Unit
Publisher
United States: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
United States: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Patients with COVID-19 present with a wide variety of clinical manifestations. Thromboembolic events constitute a significant cause of morbidity and mortality in patients infected with SARS-CoV-2. Severe COVID-19 has been associated with hyperinflammation and pre-existing cardiovascular disease. Platelets are important mediators and sensors of infl...
Alternative Titles
Full title
Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19
Authors, Artists and Contributors
Author / Creator
Sarkar, Amrita
Giannini, Heather M
Goel, Rishi R
Mathew, Divij
Suzuki, Aae
Baxter, Amy E
Greenplate, Allison R
Alanio, Cécile
Abdel-Hakeem, Mohamed
Oldridge, Derek A
Giles, Josephine
Wu, Jennifer E
Chen, Zeyu
Huang, Yinghui Jane
Pattekar, Ajinkya
Manne, Sasikanth
Kuthuru, Oliva
Dougherty, Jeanette
Weiderhold, Brittany
Weisman, Ariel R
Ittner, Caroline A G
Gouma, Sigrid
Dunbar, Debora
Frank, Ian
Huang, Alexander C
Vella, Laura A
Reilly, John P
Hensley, Scott E
Rauova, Lubica
Zhao, Liang
Meyer, Nuala J
Poncz, Mortimer
Abrams, Charles S
Wherry, E John
UPenn COVID Processing Unit
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2521276337
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2521276337
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2021.05.01.442279
