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Cephalomannine inhibits hypoxia-induced cellular function via the suppression of APEX1/HIF-1α intera...

Cephalomannine inhibits hypoxia-induced cellular function via the suppression of APEX1/HIF-1α intera...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2527361927

Cephalomannine inhibits hypoxia-induced cellular function via the suppression of APEX1/HIF-1α interaction in lung cancer

About this item

Full title

Cephalomannine inhibits hypoxia-induced cellular function via the suppression of APEX1/HIF-1α interaction in lung cancer

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2021-05, Vol.12 (5), p.490-490, Article 490

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Lung cancer (LC) is one of the leading causes of cancer-related death. As one of the key features of tumor microenvironment, hypoxia conditions are associated with poor prognosis in LC patients. Upregulation of hypoxic-induced factor-1α (HIF-1α) leads to the activation of various factors that contribute to the increased drug resistance, proliferati...

Alternative Titles

Full title

Cephalomannine inhibits hypoxia-induced cellular function via the suppression of APEX1/HIF-1α interaction in lung cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2527361927

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2527361927

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-021-03771-z

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