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Diurnal variation in neuronal chloride levels and seizure susceptibility, in neocortex, reflecting c...

Diurnal variation in neuronal chloride levels and seizure susceptibility, in neocortex, reflecting c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2527369179

Diurnal variation in neuronal chloride levels and seizure susceptibility, in neocortex, reflecting changes in activity of chloride-cation-cotransporters

About this item

Full title

Diurnal variation in neuronal chloride levels and seizure susceptibility, in neocortex, reflecting changes in activity of chloride-cation-cotransporters

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-05

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The main inhibitory synaptic currents, gated by gamma-aminobutyric acid (GABA), are mediated by Cl--conducting channels1-3, and are therefore sensitive to changes in the chloride electrochemical gradient. GABAergic activity dictates the neuronal firing range4,5 and timing6-9, which in turn influences the rhythms of the brain, synaptic plasticity, a...

Alternative Titles

Full title

Diurnal variation in neuronal chloride levels and seizure susceptibility, in neocortex, reflecting changes in activity of chloride-cation-cotransporters

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2527369179

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2527369179

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.05.12.443725