Log in to save to my catalogue

CYP3A5 and PPARA genetic variants are associated with low trough concentration to dose ratio of tacr...

CYP3A5 and PPARA genetic variants are associated with low trough concentration to dose ratio of tacr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2528317568

CYP3A5 and PPARA genetic variants are associated with low trough concentration to dose ratio of tacrolimus in kidney transplant recipients

About this item

Full title

CYP3A5 and PPARA genetic variants are associated with low trough concentration to dose ratio of tacrolimus in kidney transplant recipients

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

European journal of clinical pharmacology, 2021-06, Vol.77 (6), p.879-886

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
Genetic polymorphisms have been associated with variation in the metabolism of tacrolimus (TAC) in kidney transplant patients. This study is aimed at assessing the impact of allelic variants of
CYP3A5
and
PPARA
genes on the pharmacokinetics (PK) of TAC in Brazilian kidney transplant recipients in the first-year post-transplan...

Alternative Titles

Full title

CYP3A5 and PPARA genetic variants are associated with low trough concentration to dose ratio of tacrolimus in kidney transplant recipients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2528317568

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2528317568

Other Identifiers

ISSN

0031-6970

E-ISSN

1432-1041

DOI

10.1007/s00228-020-03076-8

How to access this item