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Long non-coding RNA SMASR inhibits the EMT by negatively regulating TGF-β/Smad signaling pathway in...

Long non-coding RNA SMASR inhibits the EMT by negatively regulating TGF-β/Smad signaling pathway in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2529007504

Long non-coding RNA SMASR inhibits the EMT by negatively regulating TGF-β/Smad signaling pathway in lung cancer

About this item

Full title

Long non-coding RNA SMASR inhibits the EMT by negatively regulating TGF-β/Smad signaling pathway in lung cancer

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2021-05, Vol.40 (20), p.3578-3592

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

TGF-β/Smad signaling pathway plays an important role in EMT during cancer progression. Long non-coding RNAs (lncRNAs) are involved in various behaviors of cancer cells, including EMT. Here, we report a novel lncRNA adjacent to Smad3, named Smad3-associated long non-coding RNA (SMASR). SMASR is downregulated by TGF-β via Smad2/3 in lung cancer cells...

Alternative Titles

Full title

Long non-coding RNA SMASR inhibits the EMT by negatively regulating TGF-β/Smad signaling pathway in lung cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2529007504

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2529007504

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-021-01760-2

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