Long non-coding RNA SMASR inhibits the EMT by negatively regulating TGF-β/Smad signaling pathway in...
Long non-coding RNA SMASR inhibits the EMT by negatively regulating TGF-β/Smad signaling pathway in lung cancer
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Author / Creator
Xu, Lele , Liu, Wenzhong , Li, Tongtong , Hu, Yuying , Wang, Yu , Huang, Lijie , Wang, Yan , Shao, Shujuan , Liu, Xuefeng and Zhan, Qimin
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
TGF-β/Smad signaling pathway plays an important role in EMT during cancer progression. Long non-coding RNAs (lncRNAs) are involved in various behaviors of cancer cells, including EMT. Here, we report a novel lncRNA adjacent to Smad3, named Smad3-associated long non-coding RNA (SMASR). SMASR is downregulated by TGF-β via Smad2/3 in lung cancer cells...
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Full title
Long non-coding RNA SMASR inhibits the EMT by negatively regulating TGF-β/Smad signaling pathway in lung cancer
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TN_cdi_proquest_journals_2529007504
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2529007504
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-021-01760-2