IL-26 mediates epidermal growth factor receptor-tyrosine kinase inhibitor resistance through endopla...
IL-26 mediates epidermal growth factor receptor-tyrosine kinase inhibitor resistance through endoplasmic reticulum stress signaling pathway in triple-negative breast cancer cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Triple-negative breast cancer (TNBC) has a poor prognosis compared to other breast cancer subtypes. Although epidermal growth factor receptor (EGFR) is overexpressed in TNBC, clinical trials with EGFR inhibitors including tyrosine kinase inhibitors (EGFR-TKI) in TNBC have heretofore been unsuccessful. To develop effective EGFR-targeted therapy for...
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Full title
IL-26 mediates epidermal growth factor receptor-tyrosine kinase inhibitor resistance through endoplasmic reticulum stress signaling pathway in triple-negative breast cancer cells
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TN_cdi_proquest_journals_2530260786
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2530260786
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-021-03787-5
