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Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth

Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2533059952

Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth

About this item

Full title

Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-05

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The Ewing sarcoma family of tumors is a group of malignant small round blue cell tumors (SRBCTs) that affects children, adolescents and young adults. The tumors are characterized by reciprocal chromosomal translocations that generate chimeric fusion oncogenes, the most common of which is EWSR1-FLI1. Survival is extremely poor for patients with meta...

Alternative Titles

Full title

Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2533059952

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2533059952

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.05.25.445683