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miRNA-126-3p carried by human umbilical cord mesenchymal stem cell enhances endothelial function thr...

miRNA-126-3p carried by human umbilical cord mesenchymal stem cell enhances endothelial function thr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2539344399

miRNA-126-3p carried by human umbilical cord mesenchymal stem cell enhances endothelial function through exosome-mediated mechanisms in vitro and attenuates vein grafts neointimal formation in vivo

About this item

Full title

miRNA-126-3p carried by human umbilical cord mesenchymal stem cell enhances endothelial function through exosome-mediated mechanisms in vitro and attenuates vein grafts neointimal formation in vivo

Publisher

Durham: Research Square

Journal title

Stem Cell Research & Therapy, 2020

Language

English

Publication information

Publisher

Durham: Research Square

Subjects

Subjects and topics

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Scope and Contents

Contents

Background: The aim of this study was to determine whether the combination of MSC implantation with miRNA-126-3p overexpression would further improve the surgical results after vein grafting. Methods: hucMSCs and HUVECs were isolated from human umbilical cords and characterized by a series of experiments. Lentivirus vector encoding miRNA-126-3p was...

Alternative Titles

Full title

miRNA-126-3p carried by human umbilical cord mesenchymal stem cell enhances endothelial function through exosome-mediated mechanisms in vitro and attenuates vein grafts neointimal formation in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2539344399

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2539344399

Other Identifiers

DOI

10.21203/rs.3.rs-64060/v2