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Genetic diagnostic features after failure of initial treatment with epidermal growth factor receptor...

Genetic diagnostic features after failure of initial treatment with epidermal growth factor receptor...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2539363948

Genetic diagnostic features after failure of initial treatment with epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors among non-small-cell lung cancer patients harboring EGFR mutations

About this item

Full title

Genetic diagnostic features after failure of initial treatment with epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors among non-small-cell lung cancer patients harboring EGFR mutations

Publisher

Durham: Research Square

Journal title

BMC Cancer, 2020

Language

English

Publication information

Publisher

Durham: Research Square

More information

Scope and Contents

Contents

Background: Osimertinib, a third-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI), can be used as second-line treatment for lung cancer patients harboring the T790M substitution. Although osimertinib is more effective than the first-generation EGFR-TKIs used for first-line treatment, its efficacy with respect to lo...

Alternative Titles

Full title

Genetic diagnostic features after failure of initial treatment with epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors among non-small-cell lung cancer patients harboring EGFR mutations

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2539363948

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2539363948

Other Identifiers

DOI

10.21203/rs.3.rs-19425/v4