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CHD4 conceals aberrant CTCF-binding sites at TAD interiors by regulating chromatin accessibility in...

CHD4 conceals aberrant CTCF-binding sites at TAD interiors by regulating chromatin accessibility in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2541569076

CHD4 conceals aberrant CTCF-binding sites at TAD interiors by regulating chromatin accessibility in mESCs

About this item

Full title

CHD4 conceals aberrant CTCF-binding sites at TAD interiors by regulating chromatin accessibility in mESCs

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-06

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

CTCF plays a critical role in the 3D chromatin organization by determining the TAD borders. Although CTCF primarily binds at the TAD borders, there also exist putative CTCF-binding sites within TADs, which are spread throughout the genome by retrotransposition. However, the detailed mechanism responsible for masking these putative CTCF-binding site...

Alternative Titles

Full title

CHD4 conceals aberrant CTCF-binding sites at TAD interiors by regulating chromatin accessibility in mESCs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2541569076

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2541569076

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.06.16.448663