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Evaluation of spontaneous seizure activity, sex-dependent differences, behavioral comorbidities, and...

Evaluation of spontaneous seizure activity, sex-dependent differences, behavioral comorbidities, and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2543467370

Evaluation of spontaneous seizure activity, sex-dependent differences, behavioral comorbidities, and alterations in CA1 neuron firing properties in a mouse model of Dravet Syndrome

About this item

Full title

Evaluation of spontaneous seizure activity, sex-dependent differences, behavioral comorbidities, and alterations in CA1 neuron firing properties in a mouse model of Dravet Syndrome

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-06

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract Dravet syndrome (DS) is a rare childhood epilepsy disorder resulting in spontaneous, recurrent seizures (SRS) and behavioral co-morbidities. To facilitate the discovery and development of anti-seizure drugs for DS, the contract site of the NINDS Epilepsy Therapy Screening Program (ETSP) has continued to evaluate a mouse model of DS. Scn1aA...

Alternative Titles

Full title

Evaluation of spontaneous seizure activity, sex-dependent differences, behavioral comorbidities, and alterations in CA1 neuron firing properties in a mouse model of Dravet Syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2543467370

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2543467370

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.06.16.448684