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EPAC1 Inhibition Protects the Heart from Doxorubicin-Induced Toxicity

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EPAC1 Inhibition Protects the Heart from Doxorubicin-Induced Toxicity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2543467546

EPAC1 Inhibition Protects the Heart from Doxorubicin-Induced Toxicity

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Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

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Scope and Contents

Contents

Anthracyclines, such as doxorubicin (Dox), are widely used chemotherapeutic agents for the treatment of solid tumors and hematologic malignancies. However, they frequently induce cardiotoxicity leading to dilated cardiomyopathy and heart failure. This study sought to investigate the role of the Exchange Protein directly Activated by cAMP (EPAC) in...

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Full title

EPAC1 Inhibition Protects the Heart from Doxorubicin-Induced Toxicity

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Record Identifier

TN_cdi_proquest_journals_2543467546

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2543467546

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.06.16.448655

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