Membrane perturbation by lipidated Atg8 underlies autophagosome biogenesis
Membrane perturbation by lipidated Atg8 underlies autophagosome biogenesis
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Autophagosome biogenesis is an essential feature of autophagy. Lipidation of Atg8 plays a critical role in this process. Previous in vitro studies identified membrane tethering and hemi-fusion/fusion activities of Atg8, yet definitive roles in autophagosome biogenesis remained controversial. Here, we studied the effect of Atg8 lipidation on membran...
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Membrane perturbation by lipidated Atg8 underlies autophagosome biogenesis
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TN_cdi_proquest_journals_2551409732
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2551409732
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/s41594-021-00614-5