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Evidence of an antidepressant-like effect of xylopic acid mediated by serotonergic mechanisms

Evidence of an antidepressant-like effect of xylopic acid mediated by serotonergic mechanisms

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2553399399

Evidence of an antidepressant-like effect of xylopic acid mediated by serotonergic mechanisms

About this item

Full title

Evidence of an antidepressant-like effect of xylopic acid mediated by serotonergic mechanisms

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Psychopharmacology, 2021-08, Vol.238 (8), p.2105-2120

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Background
Depression causes significant debilitating symptoms and economic burden. Current management is challenged by slow onset of action and modest efficacies of antidepressants; thus, the search for newer antidepressants remains relevant. We evaluated the antidepressant effects of a kaurene diterpene, xylopic acid (XA), in zebrafish and mou...

Alternative Titles

Full title

Evidence of an antidepressant-like effect of xylopic acid mediated by serotonergic mechanisms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2553399399

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2553399399

Other Identifiers

ISSN

0033-3158

E-ISSN

1432-2072

DOI

10.1007/s00213-021-05835-6

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