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Large-scale analysis of KMT2 mutations defines a distinctive molecular subset with treatment implica...

Large-scale analysis of KMT2 mutations defines a distinctive molecular subset with treatment implica...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2556149452

Large-scale analysis of KMT2 mutations defines a distinctive molecular subset with treatment implication in gastric cancer

About this item

Full title

Large-scale analysis of KMT2 mutations defines a distinctive molecular subset with treatment implication in gastric cancer

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2021-07, Vol.40 (30), p.4894-4905

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Frequent mutations of genes in the histone-lysine N-methyltransferase 2 (KMT2) family members were identified in gastric cancers (GCs). Understanding how gene mutations of
KMT2
family affect cancer progression and tumor immune microenvironment may provide new treatment strategies. A total of 1245 GCs were analyzed using next-generation sequen...

Alternative Titles

Full title

Large-scale analysis of KMT2 mutations defines a distinctive molecular subset with treatment implication in gastric cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2556149452

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2556149452

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-021-01840-3

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