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A cationic motif in Engrailed-2 homeoprotein controls its internalization via selective cell-surface...

A cationic motif in Engrailed-2 homeoprotein controls its internalization via selective cell-surface...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2556552262

A cationic motif in Engrailed-2 homeoprotein controls its internalization via selective cell-surface glycosaminoglycans interactions

About this item

Full title

A cationic motif in Engrailed-2 homeoprotein controls its internalization via selective cell-surface glycosaminoglycans interactions

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-07

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Engrailed-2 (En2) is a transcription factor that possesses as most homeoproteins the unique and intriguing property to transfer from cell to cell through unconventional pathways. The internalization mechanism of this cationic protein is far from being fully understood and is proposed to require an initial interaction with cell-surface glycosaminogl...

Alternative Titles

Full title

A cationic motif in Engrailed-2 homeoprotein controls its internalization via selective cell-surface glycosaminoglycans interactions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2556552262

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2556552262

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.07.29.454375