Deubiquitinase USP39 and E3 ligase TRIM26 balance the level of ZEB1 ubiquitination and thereby deter...
Deubiquitinase USP39 and E3 ligase TRIM26 balance the level of ZEB1 ubiquitination and thereby determine the progression of hepatocellular carcinoma
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Emerging evidence suggests that USP39 plays an important role in the development of hepatocellular carcinoma (HCC). However, the molecular mechanism by which USP39 promotes HCC progression has not been well defined, especially regarding its putative ubiquitination function. Zinc-finger E-box-binding homeobox 1 (ZEB1) is a crucial inducer of epithel...
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Deubiquitinase USP39 and E3 ligase TRIM26 balance the level of ZEB1 ubiquitination and thereby determine the progression of hepatocellular carcinoma
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TN_cdi_proquest_journals_2557304120
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2557304120
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1350-9047,1476-5403
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1476-5403
DOI
10.1038/s41418-021-00754-7
