Doxycycline host-directed therapy in human pulmonary tuberculosis
Doxycycline host-directed therapy in human pulmonary tuberculosis
About this item
Full title
Author / Creator
Miow, Qing Hao , Vallejo, Andres F , Wang, Yu , Hong, Jia Mei , Bai, Chen , Teo, Felicia S W , Wang, Alvin D Y , Loh, Hong Rong , Tan, Tuan Zea , Ding, Ying , She, Hoi Wah , Gan, Suay Hong , Paton, Nicholas I , Lum, Josephine , Tay, Alicia , Chee, Cynthia B E , Tambyah, Paul A , Polak, Marta E , Wang, Yee Tang , Singhal, Amit , Elkington, Paul T , Friedland, Jon S and Ong, Catherine W M
Publisher
Ann Arbor: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
Ann Arbor: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
BACKGROUND. Matrix metalloproteinases (MMPs) are key regulators of tissue destruction in tuberculosis (TB) and may be targets for host-directed therapy. We conducted a phase II double-blind, randomized, controlled trial investigating doxycycline, a licensed broad-spectrum MMP inhibitor, in patients with pulmonary TB. METHODS. Thirty patients with p...
Alternative Titles
Full title
Doxycycline host-directed therapy in human pulmonary tuberculosis
Authors, Artists and Contributors
Author / Creator
Vallejo, Andres F
Wang, Yu
Hong, Jia Mei
Bai, Chen
Teo, Felicia S W
Wang, Alvin D Y
Loh, Hong Rong
Tan, Tuan Zea
Ding, Ying
She, Hoi Wah
Gan, Suay Hong
Paton, Nicholas I
Lum, Josephine
Tay, Alicia
Chee, Cynthia B E
Tambyah, Paul A
Polak, Marta E
Wang, Yee Tang
Singhal, Amit
Elkington, Paul T
Friedland, Jon S
Ong, Catherine W M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2557556880
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2557556880
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI151668
