Non-Viral Engineering of CAR-NK and CAR-T cells using the Tc Buster Transposon System
Non-Viral Engineering of CAR-NK and CAR-T cells using the Tc Buster Transposon System
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Cancer immunotherapy using T cells and NK cells modified with viral vectors to express a chimeric antigen receptor (CAR) has shown remarkable efficacy in treating hematological malignancies in clinical trials. However, viral vectors are limited in their cargo size capacity, and large-scale manufacturing for clinical use remains complex and cost pro...
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Full title
Non-Viral Engineering of CAR-NK and CAR-T cells using the Tc Buster Transposon System
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TN_cdi_proquest_journals_2557923071
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2557923071
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E-ISSN
2692-8205
DOI
10.1101/2021.08.02.454772
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https://www.proquest.com/docview/2557923071?pq-origsite=primo&accountid=13902
