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Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3(ATR) kinase i...

Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3(ATR) kinase i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2559541797

Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3(ATR) kinase is essential in the absence of Rqh1(BLM) helicase

About this item

Full title

Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3(ATR) kinase is essential in the absence of Rqh1(BLM) helicase

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-08

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The Mus81-Eme1 structure-specific endonuclease is crucial for the processing of DNA recombination and late replication intermediates. In fission yeast, stimulation of Mus81-Eme1 in response to DNA damage at the G2/M transition relies on Cdc2(CDK1) and DNA damage checkpoint-dependent phosphorylation of Eme1 and is critical for chromosome stability i...

Alternative Titles

Full title

Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3(ATR) kinase is essential in the absence of Rqh1(BLM) helicase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2559541797

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2559541797

Other Identifiers

DOI

10.1101/2021.07.29.454171