Integrated annotation and analysis of genomic features reveal new types of functional elements and l...
Integrated annotation and analysis of genomic features reveal new types of functional elements and large-scale epigenetic phenomena in the developing zebrafish
About this item
Full title
Author / Creator
Baranasic, Damir , Hoertenhuber, Matthias , Balwierz, Piotr , Zehnder, Tobias , Abdul Kadir Mukarram , Nepal, Chirag , Varnai, Csilla , Hadzhiev, Yavor , Jimenez-Gonzalez, Ada , Li, Nan , Wragg, Joseph W , D'orazio, Fabio , Diaz, Noelia , Hernandez-Rodriguez, Benjamin , Chen, Zelin , Stoiber, Marcus , Dong, Michael , Stevens, Irene , Ross, Samuel E , Eagle, Anne , Ryan, Martin , Obasaju, Pelumi , Rastegar, Sepand , Mcgarvey, Alison C , Kopp, Wolfgang , Chambers, Emily , Wang, Dennis , Hyejeong Kim Kim , Acemel, Rafael D , Naranjo, Silvia , Lapinski, Maciej , Chong-Morrison, Vanessa , Mathavan, Sinnakaruppan , Peers, Bernard , Sauka-Spengler, Tatjana , Vingron, Martin , Carninci, Piero , Ohler, Uwe , Scott Allen Lacadie , Burgess, Shawn , Winata, Cecilia , Freek Van Eeden , Vaquerizas, Juan M , Gomez-Skarmeta, Jose Luis , Onichtchouk, Daria , Brown, Ben James , Bogdanovic, Ozren , Westerfield, Monte , Wardle, Fiona C , Daub, Carsten O , Lenhard, Boris and Mueller, Ferenc
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Zebrafish, a popular model for embryonic development and for modelling human diseases, has so far lacked a systematic functional annotation programme akin to those in other animal models. To address this, we formed the international DANIO-CODE consortium and created the first central repository to store and process zebrafish developmental functional genomic data. Our Data Coordination Center (https://danio-code.zfin.org) combines a total of 1,802 sets of unpublished and reanalysed published genomics data, which we used to improve existing annotations and show its utility in experimental design. We identified over 140,000 cis-regulatory elements in development, including novel classes with distinct features dependent on their activity in time and space. We del...
Alternative Titles
Full title
Integrated annotation and analysis of genomic features reveal new types of functional elements and large-scale epigenetic phenomena in the developing zebrafish
Authors, Artists and Contributors
Author / Creator
Hoertenhuber, Matthias
Balwierz, Piotr
Zehnder, Tobias
Abdul Kadir Mukarram
Nepal, Chirag
Varnai, Csilla
Hadzhiev, Yavor
Jimenez-Gonzalez, Ada
Li, Nan
Wragg, Joseph W
D'orazio, Fabio
Diaz, Noelia
Hernandez-Rodriguez, Benjamin
Chen, Zelin
Stoiber, Marcus
Dong, Michael
Stevens, Irene
Ross, Samuel E
Eagle, Anne
Ryan, Martin
Obasaju, Pelumi
Rastegar, Sepand
Mcgarvey, Alison C
Kopp, Wolfgang
Chambers, Emily
Wang, Dennis
Hyejeong Kim Kim
Acemel, Rafael D
Naranjo, Silvia
Lapinski, Maciej
Chong-Morrison, Vanessa
Mathavan, Sinnakaruppan
Peers, Bernard
Sauka-Spengler, Tatjana
Vingron, Martin
Carninci, Piero
Ohler, Uwe
Scott Allen Lacadie
Burgess, Shawn
Winata, Cecilia
Freek Van Eeden
Vaquerizas, Juan M
Gomez-Skarmeta, Jose Luis
Onichtchouk, Daria
Brown, Ben James
Bogdanovic, Ozren
Westerfield, Monte
Wardle, Fiona C
Daub, Carsten O
Lenhard, Boris
Mueller, Ferenc
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2559935281
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2559935281
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2021.08.09.454869
How to access this item
https://www.proquest.com/docview/2559935281?pq-origsite=primo&accountid=13902
