Safety and efficacy of anti-tau monoclonal antibody gosuranemab in progressive supranuclear palsy: a...
Safety and efficacy of anti-tau monoclonal antibody gosuranemab in progressive supranuclear palsy: a phase 2, randomized, placebo-controlled trial
About this item
Full title
Author / Creator
Dam, Tien , Boxer, Adam L. , Golbe, Lawrence I. , Höglinger, Günter U. , Morris, Huw R. , Litvan, Irene , Lang, Anthony E. , Corvol, Jean-Christophe , Aiba, Ikuko , Grundman, Michael , Yang, Lili , Tidemann-Miller, Beth , Kupferman, Joseph , Harper, Kristine , Kamisoglu, Kubra , Wald, Michael J. , Graham, Danielle L. , Gedney, Liz , O’Gorman, John , Haeberlein, Samantha Budd and PASSPORT Study Group
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
A randomized, double-blind, placebo-controlled, 52-week study (no. NCT03068468) evaluated gosuranemab, an anti-tau monoclonal antibody, in the treatment of progressive supranuclear palsy (PSP). In total, 486 participants dosed were assigned to either gosuranemab (
n
= 321) or placebo (
n
= 165). Efficacy was not demonstrated on adjust...
Alternative Titles
Full title
Safety and efficacy of anti-tau monoclonal antibody gosuranemab in progressive supranuclear palsy: a phase 2, randomized, placebo-controlled trial
Authors, Artists and Contributors
Author / Creator
Boxer, Adam L.
Golbe, Lawrence I.
Höglinger, Günter U.
Morris, Huw R.
Litvan, Irene
Lang, Anthony E.
Corvol, Jean-Christophe
Aiba, Ikuko
Grundman, Michael
Yang, Lili
Tidemann-Miller, Beth
Kupferman, Joseph
Harper, Kristine
Kamisoglu, Kubra
Wald, Michael J.
Graham, Danielle L.
Gedney, Liz
O’Gorman, John
Haeberlein, Samantha Budd
PASSPORT Study Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2560959688
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2560959688
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-021-01455-x
