Cardiomyocyte BRAF and type 1 RAF inhibitors promote cardiomyocyte and cardiac hypertrophy in mice i...
Cardiomyocyte BRAF and type 1 RAF inhibitors promote cardiomyocyte and cardiac hypertrophy in mice in vivo
About this item
Full title
Author / Creator
Clerk, Angela , Meijles, Daniel N , Hardyman, Michelle A , Fuller, Stephen J , Chothani, Sonia P , Cull, Joshua J , Susanna Te Cooper , Alharbi, Hajed O , Vanezis, Konstantinos , Felkin, Leanne E , Markou, Thomais , Leonard, Samuel J , Shaw, Spencer W , Owen Jl Rackham , Cook, Stuart A , Glennon, Peter E , Sheppard, Mary N , Sembrat, John C , Rojas, Mauricio , Mctiernan, Charles F , Barton, Paul J and Sugden, Peter H
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
The extracellular signal-regulated kinase 1/2 (ERK1/2) cascade promotes cardiomyocyte hypertrophy and is cardioprotective, with the three RAF kinases forming a node for signal integration. Our aims were to determine if BRAF is relevant for human heart failure, if BRAF promotes cardiomyocyte hypertrophy, and if Type 1 RAF inhibitors developed for ca...
Alternative Titles
Full title
Cardiomyocyte BRAF and type 1 RAF inhibitors promote cardiomyocyte and cardiac hypertrophy in mice in vivo
Authors, Artists and Contributors
Author / Creator
Meijles, Daniel N
Hardyman, Michelle A
Fuller, Stephen J
Chothani, Sonia P
Cull, Joshua J
Susanna Te Cooper
Alharbi, Hajed O
Vanezis, Konstantinos
Felkin, Leanne E
Markou, Thomais
Leonard, Samuel J
Shaw, Spencer W
Owen Jl Rackham
Cook, Stuart A
Glennon, Peter E
Sheppard, Mary N
Sembrat, John C
Rojas, Mauricio
Mctiernan, Charles F
Barton, Paul J
Sugden, Peter H
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2561135678
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2561135678
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2021.08.14.455637
How to access this item
https://www.proquest.com/docview/2561135678?pq-origsite=primo&accountid=13902
