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Enhancer-promoter competition between homologous alleles leads to reduced transcription in early Dro...

Enhancer-promoter competition between homologous alleles leads to reduced transcription in early Dro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2561672326

Enhancer-promoter competition between homologous alleles leads to reduced transcription in early Drosophila embryos

About this item

Full title

Enhancer-promoter competition between homologous alleles leads to reduced transcription in early Drosophila embryos

Author / Creator

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-08

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The mechanism by which transcriptional machinery is recruited to enhancers and promoters to regulate gene expression is one of the most challenging and extensively studied questions in modern biology. Here, we ask if inter-allelic interactions between two homologous alleles can affect gene regulation. Using MS2- and PP7-based, allele-specific live...

Alternative Titles

Full title

Enhancer-promoter competition between homologous alleles leads to reduced transcription in early Drosophila embryos

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2561672326

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2561672326

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.08.16.456541