Enhancer-promoter competition between homologous alleles leads to reduced transcription in early Dro...
Enhancer-promoter competition between homologous alleles leads to reduced transcription in early Drosophila embryos
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Author / Creator
Deng, Hao and Lim, Bomyi
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
The mechanism by which transcriptional machinery is recruited to enhancers and promoters to regulate gene expression is one of the most challenging and extensively studied questions in modern biology. Here, we ask if inter-allelic interactions between two homologous alleles can affect gene regulation. Using MS2- and PP7-based, allele-specific live...
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Full title
Enhancer-promoter competition between homologous alleles leads to reduced transcription in early Drosophila embryos
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TN_cdi_proquest_journals_2561672326
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2561672326
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E-ISSN
2692-8205
DOI
10.1101/2021.08.16.456541
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https://www.proquest.com/docview/2561672326?pq-origsite=primo&accountid=13902