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Stromal-cell deletion of STAT3 protects mice from kidney fibrosis by inhibiting pericytes trans-diff...

Stromal-cell deletion of STAT3 protects mice from kidney fibrosis by inhibiting pericytes trans-diff...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2562653318

Stromal-cell deletion of STAT3 protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration

About this item

Full title

Stromal-cell deletion of STAT3 protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-08

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Signal transducer and activator of transcription 3 (STAT3) is a key transcription factor implicated in the pathogenesis of kidney fibrosis. Although tubular Stat3 deletion in tubular epithelial cells is known to protect mice from kidney fibrosis, the exact function of STAT3 in stromal cells remains unknown. We utilized stromal-cell Stat3 knock-out...

Alternative Titles

Full title

Stromal-cell deletion of STAT3 protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2562653318

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2562653318

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.08.19.456872