Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant
Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Connexin-50 (Cx50) is among the most frequently mutated genes associated with congenital cataracts. While most of these disease-linked variants cause loss-of-function due to misfolding or aberrant trafficking, others directly alter channel properties. The mechanistic bases for such functional defects are mostly unknown. We investigated the function...
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Full title
Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant
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TN_cdi_proquest_journals_2562654927
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2562654927
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E-ISSN
2692-8205
DOI
10.1101/2021.08.18.456706
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https://www.proquest.com/docview/2562654927?pq-origsite=primo&accountid=13902
