Pharmacokinetics of CuGTSM, a Novel Drug Candidate, in a Mouse Model of Menkes Disease
Pharmacokinetics of CuGTSM, a Novel Drug Candidate, in a Mouse Model of Menkes Disease
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Author / Creator
Yamagishi, Yoshiaki , Kudo, Toshiyuki , Oyumi, Masafumi , Sakamoto, Yusuke , Takahashi, Kazuki , Akashi, Taiki , Kobayashi, Shohei , Kawakami, Takeaki , Goda, Hitomi , Sato, Yasuhiro , Mimaki, Masakazu , Kodama, Hiroko , Munakata, Mitsutoshi , Makino, Kosho , Takahashi, Hideyo , Fukami, Toshiro and Ito, Kiyomi
Publisher
New York: Springer US
Journal title
Language
English
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Publisher
New York: Springer US
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Scope and Contents
Contents
Purpose
Menkes disease is a rare hereditary disease in which systemic deficiency of copper due to mutation of the
ATP7A
gene causes severe neurodegenerative disorders. The present parenteral drugs have limited efficacy, so there is a need for an efficacious drug that can be administered orally. This study focused on glyoxal-bis (N(4)-methy...
Alternative Titles
Full title
Pharmacokinetics of CuGTSM, a Novel Drug Candidate, in a Mouse Model of Menkes Disease
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TN_cdi_proquest_journals_2563570675
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2563570675
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ISSN
0724-8741
E-ISSN
1573-904X
DOI
10.1007/s11095-021-03090-0
